I don't care whether it is a $2500 John Suhr or a highly modified Squier that cost you less than P20,000.
The idea of this thread is to know if you think if you had more money, would you probably be ditching your main axe now hoping for something better? Of course if you smoke through your Squier Strat now, chances are you would smoke more on a Suhr Strat. But that is not the point. By your standards, do you find your main axe perfect for your needs?
i don't think i have one main guitar. what i try to keep is one of each of the "food groups" -- strat, tele, LP, semi-hollow (+ acoustic, resonator... i also want a pedal/lap steel, btw.
. as abyss said, we like them for different reasons and applicatons. one is not better than the other, just different.
none of them are perfect, if there is even such a thing. but there are indeed a lot of better gtrs out there. so, to answer your question, yes, i would ditch my 'main' gtr in each "food group" if i had money to buy something better. heck, i've ditched gtrs for more mundane reasons (eg, "research", "not having settled on my sense of taste", etc.).