yup! i use compressors on my rig.
i keep it always on, in the beginning of my pedal chain, after the guitar. it gives the guitar a more even volume level especially when it hits the dirt. medyo mahina na lang effect nung roll-off ng volume knob if you want to clean up the dirt, pero in my case, ok lang naman since i shuffle between 2 drive pedals (crunch and OD tone, lead tone pag cascaded) so i don't really use the volume knob to clean up the tone.
matter of preference lang naman, if you want the compressed clean tone, then go get yourself one. if you love your playing dynamics, and like to play with your volume knob, i'd suggest wag ka na lang mag-compressor.
i also use the compressor to boost the signal a bit, since i use puro single coils. para mas full yung tunog ng overdrives.
the compressors i use are the HBE compressor retro (on my PT2 board) and a kalikot audio hikari comp (in my nano board)