i've recently changed to Ernie Ball 10-46s (lime green pack) on all my main guitars, but also experimented with 11-49s a while back. more bottom end, i noticed a bit more sustain and the crunch is just more defined with the heavier gauge.
and D'Addario XL-something for my Semi-Hollowbody guitar 11-49. they just sound better. and give my fingers more of a workout
note: remember to tweak the truss rod and intonation when changing gauges, just incase nobody's mentioned it