Hi X-Taxi,
The way I understand SPDIF is that it's primarily designed to carry 4 channels of audio over a single port. Now for SPDIF to carry 6 channels, audio must be compressed to fit the bandwidth of the SPDIF channel. To do this compression, you will need an encoder that would compress the audio into a format like the Dolby AC-3. Now you will not have an issue decoding this since most digital interfaces can decode AC-3. So for your question regarding the MSI mobo, yes, it might be able to output 6 channels via SPDIF.
Abusound