What i usually do is first determine the singer if it's a soprano, alto, tenor etc. Then move on with what key is the song.
Set the Retune and Tracking button initially to 50 (pag nasobrahan mo ito, hindi na natural sounding yung pagkaka correct ng notes).
Try this settings first for a start.
Remember, depende din ito sa notes na iko correct ng antares. Pag extreme na yung flats and sharps, you better adjust the notes manually in an audio editor software like soundforge.