Happy with the EMU 1820m I got from MYN11.
I currently had it maximized to 18 tracks with ADA8000 and Focusrite trackmaster. Works great on my windows XP set up without any whims. I got used to how to work with patchmix. Even using the DSP effects.
Cons - This unit got damaged a few months ago with busted capacitors. But I did a thorough research on it and fixed it myself. Bought the capasitors on ebay and still have a few extras just in case it conks out again. Any EMU users with the same problem PM me I can help out.
I also am starting to enjoy my couple MOTU 2408 with ADA8000 and Octane. The Cuemix was familiar to me after using patchmix for years.
Cons: No Midi port for my mackie control unit. Good thing I kept my usb midi. Need a lot of preamps adat preamps with this.
I also have an Echo layla which I am not using anymore since I only have two PCs in the studio.
If you notice, all my interfaces are PCI based. I feel comfortable with them rather than USB. I think they are more stable when you get to have the right (compatible) hardware.
I still have an old MBOX which is USB only for the purpose of running Protools LE when I get to recieve a protools project. But this will be going away as soon as I get my protools 10 next month.
If you notice my interface has a lot of inputs that is because that is what I need. So the selection of interface would be according to what you need and how you will be using it. Portable or fixed? Variety of mics / preamps for a variety of applications?