I don't think PT will readily accept signals from 2 disparate pieces of gear esp. if one is pci and the other is firewire. I've read that some have been able to make two 1010's work, but you still get a max of 18 channels in 44.1/48 khz. I think the better bet would be to use the 2626 exclusively and add something like the Behringer ADA8000 (or better) to the Profire's ADAT I/O for more inputs.